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Lower the Risk of Alzheimer's Disease by Eating Omega-3s

Joseph Coupal - Friday, May 04, 2012

Most people have heard that a diet rich in Omega-3s is good for you. But according to new research, eating foods such as chicken, fish and nuts may help lower blood levels of a protein strongly associated with Alzheimer's disease and memory problems.

In the Columbia University study, people who consumed diets rich in omega-3 fatty acids had significantly lower levels of a protein called beta-amyloid in their blood than those who did not consume as much of the nutrient.
 
According to the research, eating one more gram of omega-3s than average per week was associated with 20 to 30% lower levels of beta-amyloid.  One gram is approximately equal to half a fillet of salmon.

However, study author Dr. Nikolaos Scarmeas, a neurologist at Columbia University Medical Center recommended not focusing on eating particular quantities of omega-3s, but rather, incorporating as much of the nutrient into one’s diet as possible.

If two people consumed the same amount of omega-3s, one through food and the other through supplements, the person who consumed more omega-3 rich foods typically had lower blood levels of beta-amyloid.

It is believed that the build-up of beta-amyloid in the brain, not the blood, is a precursor for Alzheimer's.  However, past studies have indicated there may be a relationship between blood levels and brain levels of the protein.

“There is complex, conflicting literature; we do not understand very well biologically how levels of beta-amyloid in the blood, brain and spinal fluid are related exactly,” Scarmeas said. "In some studies, higher levels of beta-amyloid in the blood relate to higher levels of beta-amyloid in the brain.  Other studies have suggested the opposite."

Scarmeas added that his own lab had observed that people with higher blood levels of beta-amyloid were more likely to develop dementia, while people with lower levels tended not to.

The beneficial impact of omega-3 on brain health would fall in line with past studies of the nutrient.  Omega-3s have long been associated with positive benefits for memory and cognition.

Scarmeas speculated that omega-3s may be able to reduce oxidative stress on the brain and the resulting vascular damage, or even have some kind of impact on beta-amyloid in the brain. Though, there is not enough support yet to suggest the nutrient and protein are directly related.

"Previous studies have suggested that omega-3s and other aspects of diet may be related to brain function," he said. "Here we demonstrate one possible mechanism could be through amyloid, the main biological mechanism that relates to Alzheimer's disease. There have been animal studies suggesting omega-3s could relate to amyloid brain biology.  We've demonstrated this association may also be present in humans."

The study was published Wednesday in the journal Neurology.

Fox News

Safeguard Your Brain Against Memory Loss

Joseph Coupal - Monday, April 23, 2012

Johns Hopkins is now presenting a quarterly in-depth report on the latest scientific breakthroughs, research findings and medical discoveries to help you safeguard your brain against aging and memory loss.

There are many exciting developments in the fields of Alzheimer's and memory research, and there's no better way to access this information than a subscription to the Johns Hopkins Memory Disorders Bulletin. Each quarterly issue brings critical information for patients and caregivers on Alzheimer's disease, dementia, Lewy body dementia, vascular dementia and other memory conditions. Edited by Dr. Peter V. Rabins, director of the division of Geriatric and Neuropsychiatry at the Johns Hopkins School of Medicine and author of the widely read book The 36-Hour Day, the Johns Hopkins Memory Disorders Bulletin contains the latest scientific breakthroughs, research findings from the world's foremost medical journals and conferences, news of medications and caregiver support, plus medical discoveries for safeguarding your brain against aging and memory loss. When you subscribe today, you'll get four FREE Special Reports to download instantly.

Order here

Johns Hopkins Health Alert

The Aging Brain is not Beyond Repair

Joseph Coupal - Monday, April 16, 2012

Research is changing what we know about our Grey Matter. Our brains continue to produce brain cells into our 70’s. Because of changes in technology, science is making progress in cognitive science. Cognitive loss and forgetfulness is largely preventable.

According to a study, baby boomers now fear Alzheimer’s more than any other illness. The biggest question in age related memory decline is: how much it affects your daily life. The other is:  is memory decline getting gradually worse?

Those over 50 naturally experience age related memory decline.

How can you tell the difference between natural forgetfulness and Alzheimer's, and how can you prevent it?  The brain is resilient and recent science shows how the brain can change and grow even while aging. Watch the following video.

Dementia Cases Will Triple by 2050 Says the WHO

Joseph Coupal - Thursday, April 12, 2012

Cases of dementia — and the heavy social and financial burdens associated with them — are set to soar in the coming decades as life expectancy and medical care improve in poorer countries, the World Health Organization says.

Some 35.6 million people were living with dementia in 2010, but that figure is set to double to 65.7 million by 2030, the U.N. health agency said Wednesday. In 2050, it expects the number of dementia cases to triple to 115.4 million.

Most dementia patients are cared for by relatives, who shoulder the bulk of the current estimated annual cost of $604 billion, WHO said.

"The catastrophic cost drives millions of households below the poverty line," warned the agency's director-general, Margaret Chan.

Dementia, a brain illness that affects memory, behavior and the ability to perform common tasks, affects mostly older people. About 70% of cases are believed to be caused by Alzheimer's.

In the last few decades dementia has become a major public health issue in rich countries. But with populations in poor and middle-income countries projected to grow and age rapidly over the coming decades, the agency appealed for greater public awareness and better support programs everywhere.

The share of cases in poor and middle-income countries is expected to rise from just under 60% today, to over 70% by 2050.

So far, only eight countries — including Britain, France and Japan — have national programs to address dementia, WHO said. Several others, such as the United States, have plans at the state level.

WHO said a lack of proper diagnosis is one of the obstacles to better dementia treatment. Even in rich countries more than half of dementia cases are overlooked until the disease has reached a late stage.

USA Today

Earlier Diagnosis of Alzheimer's is Possible With New Brain Protein Test

Joseph Coupal - Monday, April 09, 2012

A much-anticipated test developed by Eli Lilly that detects the presence of proteins in the brain that are related to Alzheimer's disease was approved by the US Food and Drug Administration.

This test could enable clinicians to detect Alzheimer's earlier and more accurately in patients at the earliest sign of memory problems -- a potential boon to treatment and developing drugs against the disease.

The test uses a chemical known by the brand name Amyvid, a radioactive agent that tags clumps of a sticky substance called an amyloid. Amyloid proteins are hallmarks of Alzheimer's disease. The chemical is then detected using a brain imaging technique called positron emission tomography, known as PET scans.

For patients who already have some symptoms of cognitive decline, a positive scan suggests that moderate to frequent amyloid plaques are present in the brain, which is consistent with Alzheimer's disease.

If the scan is negative, indicating no clumps or few clumps of amyloid, "that gives the clinician a clue that Alzheimer's is less likely to be the cause of those symptoms," according to Daniel Skovronsky, who developed the agent at Lilly. For those patients, doctors can look for other potential causes of the memory decline, which may have another prognosis or be treated differentially than Alzheimer's.

The imaging agent cannot be used to diagnose someone with Alzheimer's disease if the individual does not experience memory impairment because the presence of amyloid in the brain does not alone suggest that someone has Alzheimer's.

Before the development of imaging agents, amyloid plaques could be determined only after death, by examining the brain during an autopsy.

Some 20% of cognitively healthy older adults have been found during autopsies to have large quantities of amyloid in the brain.

"It is likely to play an important role in learning both how to diagnose and treat the disease, but it's still an open question at this point for asymptomatic people," according to Park, a behavioral and brain-sciences professor who uses Amyvid in her research on aging of healthy older adults.

Amyvid will be available in limited quantities starting in June after being approved Friday, Lilly said.

Wall Street Journal

How to Consider Alzheimer's Assisted Living Communities

Joseph Coupal - Monday, December 12, 2011

Assisted living communities provide a type of housing for people who need various levels of medical and personal care. The goal of Spring Arbor Living is to provide a home-like setting and is designed to promote the patients’ independence. Services are offered to assist residents with daily living.

What Services Do Assisted Living Communities Provide?
Generally the services provided by assisted living communities vary from facility to facility. Services in various facilities often include:

  • One to three meals a day
  • Monitoring of medication
  • Personal care, including dressing and bathing
  • Housekeeping and laundry
  • 24-hour emergency care
  • Varying medical services
  • Social and recreational activities


How Can I Know What Services my Loved One Needs?
Talk with your family, caregivers and patient about what services are needed from an Alzheimer’s Care Facility. Take time to consider what services are important before you visit the assisted living communities. This will help ease the transition. Think about these questions:

  • How soon do you want/need to change the patients’ residence?
  • What daily activities do they need help with (bathing, dressing, toileting, eating)?
  • How often do they need help?

For more information or to set up an appointment contact Spring Arbor Living in your area.

Research Update: Dementia Linked to Atrial Fibrillation

Joseph Coupal - Monday, November 21, 2011

As our population ages, people with chronic cardiovascular disease, including atrial fibrillation (or irregular heartbeat), are living longer. In a study reported in the journal Heart Rhythm (Volume 7, page 433) researchers reported that atrial fibrillation may be associated with an increased risk of developing dementia and Alzheimer's disease.

Over 37,000 people, average age 60, from the ongoing Intermountain Heart Collaborative Study database were evaluated for signs of atrial fibrillation and for Alzheimer's disease or vascular, senile or nonspecific dementia. During an average of five years' follow-up, 4 percent developed dementia and 27 percent developed atrial fibrillation.

Atrial fibrillation was associated with each of the four types of dementia, independent of other cardiovascular diseases. The youngest group with atrial fibrillation (under age 70) had the highest risk of dementia; dementia is linked to older age, so this finding suggests the relationship between atrial fibrillation and dementia is particularly strong. Atrial fibrillation was also linked with the highest risk of death.

Take away: Because subjects with atrial fibrillation were identified as having higher risks of dementia and death, people with cardiovascular diseases -- who are urged to consider measures like diet, exercise, medication and avoiding tobacco for their heart disease -- might want to take these steps also to prevent or delay the development of Alzheimer's.

All the facts you need to make informed decisions if you have to confront Alzheimer's disease -- the most common cause of dementia

Written by Dr. Peter V. Rabins, director of the Division of Geriatric and Neuropsychiatry at the Johns Hopkins School of Medicine and Medical Editor of the Johns Hopkins Memory Bulletin, Diagnosing and Treating Alzheimer's Disease is an indispensable resource for anyone concerned about Alzheimer's disease. This new report provides all the facts you need to make informed decisions if you have to confront Alzheimer's disease. You'll learn how Alzheimer's is currently diagnosed ... the existing drugs that are used to treat it ... and various new therapies that may someday provide better treatment.

Very Early Signs and Symptoms of Alzheimer's

Joseph Coupal - Friday, November 11, 2011

Memory problems are typically one of the first warning signs of cognitive loss, possibly due to the development of Alzheimer’s disease. Some people with memory problems have a condition called amnestic mild cognitive impairment (MCI). People with this condition have more memory problems than normal for people their age, but their symptoms are not as severe as those seen in people with Alzheimer’s disease. Other recent studies have found links between some movement difficulties and MCI.

Researchers also have seen links between MCI and some problems with the sense of smell. The ability of people with MCI to perform normal daily activities is not significantly impaired. However, more older people with MCI, compared with those without MCI, go on to develop Alzheimer’s.

A decline in other areas of cognition, such as word-finding, vision/spatial issues, and impaired reasoning or judgment, may also signal the very early stages of Alzheimer’s disease. Scientists are looking to see whether brain imaging and biomarker studies of people with MCI and those with a family history of Alzheimer’s, can detect early changes in the brain like those seen in Alzheimer’s.

Initial studies indicate that early detection using biomarkers and imaging may be possible, but findings will need to be confirmed by other studies before these techniques can be used to help with diagnosis in everyday medical practice.

These and other studies offer hope that someday we may have tools that could help detect Alzheimer’s early, track the course of the disease, and monitor response to treatments.

Excerpt – National Institute on Aging

Tips for Caregiver Stress

Joseph Coupal - Monday, November 07, 2011

Taking care of a relative suffering from Alzheimer’s can be trying, stressful and emotional as the disease progresses.

Yet many families want to keep their relative close, and provide the best care they can from home. It’s important to remember, however, that you can’t care for someone else if you get too run down yourself.

Here are some tips for caregivers that can help you stay healthy and be better able to provide the patience and understanding necessary to the care of their loved one.

1. Share the responsibility. Being the sole person responsible for your loved one’s care can be too much. When you’re run down, stressed out or frustrated you won’t be a good caregiver, and you won’t be doing yourself any favors. Going on too long without a break can lead to emotional and physical health deterioration in your health. Get other family members to help so you have time to yourself as well.

2. Take time for yourself. Make time for the activities that you love at least once a week. Lowering your stress levels will reduce your risk of illnesses and make you feel mentally better. You also want to make sure that you’re nurturing your relationship with your children and family. Caring for a loved one takes a lot of time, but spend time with others as well.

3. Don’t blame yourself. When caring for someone with a disease like Alzheimer’s, accidents will inevitably happen now and again no matter how careful you are. Don’t put all the blame on yourself and further stress yourself out. If you’re doing the best you can, understand that you cannot plan for or prevent every possibility. Learning to relax a little and step back will give you some perspective and lower your stress levels.

4. Join a support group. Don’t go through the stress of caring for someone with Alzheimer’s alone. Caretakers can find support groups. There are numerous websites and blogs dedicated to providing advice, support and laughs to lighten the mood. Finding emotional support is key to keeping yourself mentally healthy and able to care for your loved one.

While being a caregiver can sometimes feel like an all-consuming task, it’s important to pull out a few moments each day to think about yourself and your health. If you are happy, healthy you will be able to provide care and take care of your life as well.

Understand that there are Alzheimer’s care facilities that can meet your needs where your loved one can be happy. Contact Spring Arbor Living in your area for information when the time comes where you feel you or your loved one may be better off with professional care.
 
Original article – Alzheimer’s Reading Room

When it is Time to Choose an Alzheimers Care Facility

Joseph Coupal - Friday, November 04, 2011

Alzheimer's is the most common type of dementing disease afflicting the elderly. There are approximately 4 million people suffering from this disease. The millions of people who suffer from this disease must be cared for either at home or in a care facility.

Caring for an Alzheimer's patient at home

About two thirds of those suffering from this disease are cared for at home by family, usually a spouse. As the disease progresses it carries with it a huge burden both physically and psychologically on the care givers. It is vital that the care giver access support systems that can provide reassurance, support groups, literature and strategies for coping with someone who has the disease.
 
Too often the strain becomes too much for a spouse trying to cope all alone with an Alzheimer's sufferer and they themselves have a physical or mental breakdown.

Choosing the right type of care facility

As the burden of care increases many families seek care for their family member outside the home. Finding the right Alzheimer’s care facility can be a difficult process encompassing many concerns.

Understanding the level and type of care facility where your family member is most appropriately cared for is critical. Choosing Assisted Living communities with levels of care is important. Too often families will place an Alzheimer sufferer at the wrong level, either in a facility that offers more assistance than the family member needs or worse making the family member cope with living in a facility that doesn't have the necessary support services required to meet their needs.

Contact Spring Arbor in your area. We understand the needs of those suffering from Alzheimer’s disease we can match their needs with our custom care plans.


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