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Up to half of Alzheimer's disease cases worldwide are potentially attributable to seven preventable risk factors, a new study suggests. 

The findings show that Alzheimer's cases could be reduced if people quit smoking, increased their physical activity, enhanced their mental activity, controlled their blood pressure and diabetes, and managed their obesity and depression. 

The top 3 factors

In this study by University of California, San Fransisco, the authors reviewed previous research that examined factors that predispose people to developing Alzheimer's. They identified seven factors that were potentially within a person's control to change. 

Enhancing mental activity could make the biggest difference in developing Alzheimer's. That's because the study showed "low educational attainment" was the factor that impacts the largest portion of Alzheimer's cases worldwide. They defined low educational attainment as not completing higher education, having a low IQ or not participating in mentally stimulating leisure time activities, and found it contributes to 19% of Alzheimer's cases, or 6.5 million cases worldwide. 

Smoking contributes to the second-highest number of cases, 14% of cases, or 4.7 million cases worldwide.
Physical inactivity contributed to 13% of worldwide cases and was the third-largest factor. However, it was the highest contributor to cases in the U.S. — contributing to 21%, or 1.1 million cases. 

What really mattered was how common the risk factors were in the population. In the U.S., about a third of the population is sedentary, so a large number of Alzheimer's cases are potentially attributable to physical inactivity. 

However, worldwide, low education was more important, because so many people throughout the world are illiterate or are not educated beyond elementary school. And, smoking also contributed to a large percentage of cases worldwide because it is still very common. 

This suggests that smoking cessation and initiatives to increase physical activity could dramatically decrease  the number of Alzheimer's cases. 

A note of caution

It has been noted that while these seven factors may contribute to the development of Alzheimer's, none of the factors have been shown to cause the disease. 

However, the findings suggest "that preventive and therapeutic interventions have great potential," and that interventions should be carried out in high-risk populations. 

Globally, an estimated 33.9 million people have Alzheimer's, but that number could be reduced by 3 million if there was a 25% reduction in all seven of these risk factors. A 10% reduction in these seven factors could prevent 1.1 million cases. The number of worldwide cases is expected to triple over the next 40 years.

The results of the study were presented July 20 at The Alzheimer's Association 2011 International Conference on Alzheimer's Disease (ICAD), held in Paris. The study was simultaneously published online in the journal The Lancet Neurology. 

Original article on MSNBC.com

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As we age and our memory starts to fade, we all worry about our mental health and the potential for cognitive decline. But maintaining our mental health may not be any harder than going for a walk. A new, nine year study found that walking can keep dementia at bay. So put on your sneakers and go for a walk. Walking six miles a week protects the brain from shrinkage, which may slow the progress of cognitive decline.

Brain size shrinks late in adulthood which often is the start of dementia. Other studies suggest that physical activity protects against the deterioration of brain tissue, but no long-term studies have tested that theory. A study from the University of Pittsburgh wanted to do just that.

They asked 299 healthy, dementia-free men and women, average age 78, to keep track of the number of blocks they walked in a week.

After nine years, the researchers measured the brain size of the participants using high-resolution brain scans. The men and women who walked more had more gray matter. Those who walked approximately six to nine miles a week fared best, even after taking into account variables such as age, sex, body mass index and education. Walking more than 6-9 miles in a week didn't provide extra benefits.

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We expect our joints and lungs to slowly decline as we age, but the thought of our minds doing the same is scary. Here are some ideas to help prevent brain decline.

Scientists are starting to think that regular aerobic exercise may be the single most important thing you can do for the long-term health of your brain. While the heart and lungs respond loudly to  the treadmill, the brain is quietly getting fitter with each step, too. For mental fitness, aim for at least 30 minutes of physical activity every other day.

Too much or too little energy throws a kink in the brain’s delicate machinery. A low glycemic diet — high fiber, with moderate amounts of fat and protein — is broken down more slowly in the body. A steady pace of digestion in the gut gives a more reliable flow of energy to the brain, optimizing the organ’s long-term health and performance.

Largely preventable diseases — such as Type II diabetes, obesity and hypertension — affect your brain. System-wide health concerns have been linked to an increased risk of cognitive decline and memory impairments. Keeping your circulatory system in working order by avoiding cigarettes and saturated fat, lessens the onslaught of age-related brain wear and tear.

When we don't sleep, proteins build up on synapses, possibly making it hard to think and learn new things. Furthermore, chronically sleeping poorly (in contrast to not enough) is linked to cognitive decline in old age, although the relationship may not be causal.

Growing evidence suggests a caffeine habit may protect the brain. According to large longitudinal studies, two to four perk-me-ups a day may stave off normal cognitive decline and decrease the incidence of Alzheimer's by 30 to 60 percent. It is unclear whether the benefits come from caffeine or the antioxidants found in coffee and tea, but that latte may improve cognition this afternoon and several decades from now.

Some theories credit the introduction of fish into the human diet with the evolution of our tremendous cognitive ability. Fatty acids, such as Omega 3s, are critical to brain function and are proving beneficial for treating such brain-sapping ailments as depression. Studies on the efficacy of Omega 3 supplements, however, have had mixed results, so get doses from food sources, such as flax seeds, fatty fish and grass-fed animals.

Stress takes a toll on the brain by washing harmful chemicals over the hippocampus and other brain areas involved in memory. Some scientists suspect that living a balanced lifestyle and pursuing relaxing activities such as yoga, socializing and crafting may delay memory impairment by reducing stress.

Whether crossword puzzles, sudoku and other brain teasers actually keep your brain in shape, has not been well-established. However, lack of education is a strong predictor of cognitive decline. The more you've tried to learn, the better you'll be at mental sit-ups in old age. 

Information from Live Science

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One day your doctor might give you this prescription to prevent Alzheimer’s: Eat less red meat and sugar; eat more fruits, vegetables, fish and olive oil.

At least that seems to be the finding of a new study that found that eating a diet low in saturated fat and sugary treats can improve your memory and may reduce your risk of developing dementia.

Researchers with the University of Washington and Veterans Affairs Puget Sound medical center decided to see if a change in diet could affect the risk for Alzheimer’s or benefit those already suffering some mild but early symptoms of the disease.

What they found was that a diet rich in fruits, vegetables, grains, fish and olive oil can improve some memory skills in both healthy older adults, as well as those already experiencing cognitive difficulty.

More importantly, eating this kind of diet can help healthy adults reduce their risk of developing dementia, says study researcher Suzanne Craft with the Memory Wellness Program at the VA.

Researchers found that after four weeks on the low-fat diet, subjects had fewer toxic proteins and evidence of inflammation in their spinal fluid, both considered to be bio-markers for Alzheimer’s, Craft said.

“I like to think of this kind of diet as promoting healthy brain aging, as well as reducing the risk of Alzheimer’s,” she said.

The Washington state researchers wrote that they decided to take a “whole-diet” approach, rather than focus on a single dietary component, such as omega-3 fish oil. They also chose to test the subjects’ spinal fluid for bio-markers because of the importance of the central nervous system to brain health.

The 49 subjects, all older than 60, included 20 healthy adults with no signs of memory decline, and 29 who were at high-risk for Alzheimer’s, having already been diagnosed with some cognitive impairment.

They were randomly selected to either follow a four-week low-saturated fat, high-fiber plan similar to a Mediterranean diet, or a four-week high-saturated fat diet that included foods like red meat, butter, french fries and soda.

Both groups ate the same amount of protein and the diets were balanced so subjects did not lose or gain or weight.

However, for those who want to protect their brain health, it seems pretty clear from these preliminary results that eating a healthy diet is a powerful first step.

Original article on AARP

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An older person who cares for a spouse with dementia is also at an increased risk of developing problems with attention and memory, according to a new review of studies.

This is because the spousal caregiver likely shared lifestyle risk factors with the person with dementia, and undergoes ongoing stress from caring for the person.

Researchers from the University Of Washington School Of Medicine reviewed more than 100 studies that examined the cognitive health of older adults who cared for a family member with dementia, with the majority of the subjects being spouses. They found that these caregivers have more trouble with attention and memory, also known as cognition, than people who don't have to care for a family member with dementia.

The review of the studies showed that those caregivers had a higher risk of cognitive decline or dementia than people who do not have to care for someone with dementia. This could be due to a number of factors, including depression, loneliness, sleep problems, social isolation, exercise, diet and even obesity.

People who are caring for a spouse with dementia may themselves be at risk for cognitive problems which, in turn, will not only negatively influence their quality of life, but may reduce their ability to provide the necessary care for their spouse.

Most care-recipients prefer to be cared for in their homes, and, by remaining in their homes, health care costs are reduced greatly, therefore, often spouses of end up providing care.

The study was published in the Journal of the American Geriatrics Society.

People with dementia are not the only ones who have health problems – a spouse who cares for them are also at risk for attention and memory problems.

Original article on MSN.com

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